产品货号：
Z13491
中文名称：
CHMP4B抗体
英文名称：
Anti-CHMP4B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CHMP4B Antibody |
| 指标别名 | C20orf178;CHMP4B;chromatin modifying protein 4B;CTPP3;hSnf7 2;hVps32 2;Shax1;SNF7;SNF7 2;Vps32 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,Direct ELISA |
| 基因名称 | CHMP4B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CHMP4B recombinant protein (Position:G5-M224). |
| 实际分子量 | 33KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family.The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III),which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes.The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1.The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP,also known as ALIX),which also functions in the ESCRT pathway.The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding.These polymers are proposed to help generate the luminal vesicles of multivesicular bodies.Mutations in this gene result in autosomal dominant posterior polar cataracts. |
| Uniprot ID | Q9H444 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Direct ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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